Module |
Function |
Haplogroup classification module |
classify haplogroup according to mtDNA control region sequence |
classify haplogroup according to variants in mtDNA control region |
classify haplogroup according to the mtDNA genome sequence lacking D-loop region |
classify haplogroup according to variants in the mtDNA genome lacking D-loop region |
classify haplogroup according to the whole mtDNA genome sequence |
classify haplogroup according to variants in the whole mtDNA genome |
transform variants between rCRS as reference seq. and RSRS as reference seq. |
Detailed parsing module |
display the location of the variant |
display interspecies conservation index of the variant |
display change of amino acid status |
identify potentially pathogenic mutations based on the literatures |
scan possible errors with the help of speculated haplogroups |
Database module |
retrieve and download mtDNA genomes of multiple species |
retrieve and download human complete mtDNA sequences |
retrieve pathogenic mutations in human mtDNA |
retrieve human mitochondria-located proteins |
retrieve haplogroup-specific variation motifs |
Statistical analysis module |
perform Fisher’s exact test |
perform Pearson’s Chi-square test |
perform Yates’ Chi-square test |